Western Medicine Dry Granulation Roll Compactor for strict process requirements

The dry granulation process is used to form granules without using a liquid solution because the product to be granulated may be sensitive to moisture and heat. Forming granules without moisture requires compacting and densifying the powders.

The dry powders can be compressed using a conventional tablet machine or, more usually, a large heavy-duty rotary press can be used. This process is often known as ‘slugging’, the compact made in the process (typically 25 mm diameter by about 10–15 mm thick) being termed a ‘slug’. A milling device is suitable for breaking the compacts. Roller compactors Roller compaction is an alternative gentler method, the powder mix being squeezed between two rollers to form a compressed sheet. The sheet normally is weak and brittle and breaks immediately into flakes. These flakes need gentler treatment to break them into granules. This can further be milled into desired particle size.

Roller Compactor For Dry Granulation has the following features:

• In compliance with cGMP guidelines
• Contact parts are made of S.S 304 or S.S. 316 except rollers
• All covers are designed to obtain dust-free operation
• Feed screw is steplessly driven through variable frequency drive.
• Hard chome plated & mirror finished compacting rolls made of tools steel
• Pre-compaction chamber guides the product to rolls without any slippage or leakage.
• Electrical interlocking between main roll drive and feed screw drive
• Water Jacketing arrangement
• Hydraulic Power Pack system
• Inverter for rolls and milling device
• PLC system as per 21 CFR part 11 (optional)