Reagents For Serum Amyloid A(SAA) Clinical Significance In
Pediatrics / Neonatology
SAA Overview
Serum amyloid A (SAA) is an acute phase reactive protein secreted
by the liver. When virus or bacterial infection occurs, SAA will
increase significantly within 3 ~ 6 hours, even hundreds of times
in the acute phase. The half-life of SAA is very short and will
decay rapidly during rehabilitation. It is more sensitive than CRP.
The combination of the two can better distinguish the types of
infection and improve the diagnostic efficiency of viral infection.
SAA performance index
| Detection range | sample size | Sample type | Test time |
| 5~200mg/L | 5μl | Whole blood / serum / plasma | 3min |
Clinical Significance Of SAA
Dynamic monitoring
Prognosis evaluation
Guiding medication
| Virus infection sensitivity index | SAA is more sensitive than CRP. The combined detection of CRP and
SAA is helpful to identify early infectious diseases. |
| Transplant rejection test indicators | Studies have shown that SAA is one of the early indicators of
rejection and can be used as a sensitive indicator for early
detection of graft rejection. |
| Monitoring indicators of tumor invasion and metastasis | SAA increased in different degrees in patients with various tumors,
and its level was significantly correlated with tumor activity,
malignancy, invasion and metastasis, which can be used as one of
the indicators of dynamic monitoring |
| Predictors of cardiovascular events | The increase of SAA concentration is positively correlated with the
possibility of cardiovascular events in healthy people in the
future, so SAA can be used as a predictor and prognostic index of
cardiovascular events. |
| Diagnostic indicators of AA amyloidosis | SAA is a precursor of AA and plays a key role in pathogenesis. The
long-term maintenance of serum SAA level at high concentration can
be used as an indicator of SAA treatment and prognosis |
Comparison Of CRP And SAA
| Index | CRP | SAA |
| Time of discovery | 1930 | 1976 |
| Clinical features | Increased bacterial infection 30% increase in viral infections | Virus infection is significantly increased Large increase in bacterial infections Infection cure has dropped significantly |
| Peak time | Rising period: 4-6 hours Platform period: 24-48 hours Half life: 18 hours | Rising period: 3-6 hours Platform period: 5-6 hours Half life: 50 minutes |
Application Department
Laboratory, emergency, ICU, Pediatrics / neonatology, respiratory,
surgery, hematology, rheumatology and immunology, oncology,
Nephrology, etc.
Clinical comparison of SAA
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise
engaged in the research and development, production and operation
of in vitro diagnostic products. The in vitro diagnostic products
developed by the company cover POCT series, microbial series,
biochemical series and immune series reagents and supporting
instruments.
The company has always adhered to the core concept of "fast and
accurate, living up to life", committed to providing society with
excellent products and services, and contributing to the cause of
human health.
