Cystatin C Detection Reagent (Immunofluorescence Chromatography)
(CysC) Performance Index
CysC overview
The cysteine proteinase inhibitor (CPI) is known as cystatin C.
Cycle in inhibition of C is cleared after the glomerular
filtration, only is a kind of endogenous markers to reflect the
actual changes in glomerular filtration rate, and in the proximal
convoluted tubule reuptake, but were completely after heavy
absorption metabolism decomposition, do not return the blood,
therefore, its blood concentration is determined by glomerular
filtration rate, and not dependent on any external factors, such as
gender, age, diet, It is an ideal endogenous marker to reflect the
change of glomerular filtration rate.
CysC performance index
| Detection range | sample size | Sample type | Test time |
| 0.2~8mg/L | 10μl | Whole blood / serum / plasma | 15min |
Clinical significance of CysC
- The ideal endogenous marker for GFR
- Early diagnosis and monitoring of renal diseases
- Renal function assessment in high-risk groups for AKI
Comparison of sensitivity of cystatin C and serum creatinine to
assess GFR
| | Cystatin C | Cystatin C |
| creatinine | |
| GFR(mL/min/1.73m2) | >89 | 60-89 | 30-59 | 15-29 | <15 |
| CKD stage | 1 | 2 | 3 | 4 | 5 |
| | Renal impairment with normal/elevated GFR | Mild renal insufficiency | Moderate renal insufficiency | Severe renal insufficiency | Stage Renal Disease (ESRD) |
Application Department
Internal medicine, pediatrics, orthopedics, cardiology, gynecology,
obstetrics and Gynecology, emergency, ICU, Nephrology,
Clinical comparison of CysC
Company profile
Zhongxiu Science And Technology Co.,Ltd., is a high-tech enterprise
engaged in the research and development, production and operation
of in vitro diagnostic products. The in vitro diagnostic products
developed by the company cover POCT series, microbial series,
biochemical series and immune series reagents and supporting
instruments.
The company has always adhered to the core concept of "fast and
accurate, living up to life", committed to providing society with
excellent products and services, and contributing to the cause of
human health.
